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Some individuals may experience minor digestive discomfort when starting a new supplement

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For instance, in the BRIDGE trial comparing DMF alone to a compound containing DMF plus other FAE, while both were significantly more effective than a placebo, there was no significant difference between them, indicating that DMF is the active ingredient in terms of efficacy

Acta Physico-Chimica Sinica, 28, 1777-1782

Pharmacological preconditioning with nicorandil and pioglitazone attenuates myocardial ischemia/reperfusion injury in rats